Vicodin ES 7.5/750 mg is a specific, high-strength formulation containing 7.5 mg of hydrocodone bitartrate and 750 mg of acetaminophen. While the "ES" (Extra Strength) version was widely prescribed for many years, it is important to note that as of 2014, the FDA requested manufacturers to limit the amount of acetaminophen in prescription combination products to no more than 325 mg per... https://medznow.com/pain-relief/vicodin-es-75-750-mg/