Nonessential tRNA modifications by methyltransferases are evolutionarily conserved and have been reported to stabilize mature tRNA molecules and prevent rapid tRNA decay (RTD). The tRNA modifying enzymes. NSUN2 and METTL1. are mammalian orthologs of yeast Trm4 and Trm8. https://chefesquipmenters.shop/product-category/platform-trucks/