The human CLCA4 (chloride channel regulator. calcium-activated) modulates the intestinal phenotype of cystic fibrosis (CF) patients via an as yet unknown pathway. With the generation of new porcine CF models. species-specific differences between human modifiers of CF and their porcine orthologs are considered critical for the translation of experimental data. https://yeswellneses.shop/product-category/nasal-spray/